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Home » Healthcare » Protein Expression Market Size, Global Industry Report, 2030

Protein Expression Market By Product and Service (Reagents, Expression Vectors, Competent Cells, Instruments, Services), By Application (Therapeutic Applications, Industrial Applications, Research Applications), By End-User (Pharmaceutical and Biotechnology Companies, Academic Research Institutes, Contract Research Organizations (CROs), Other End Users), By Geography, Size, Share, Global Industry Report, Forecast, 2021-2030

Published On: Apr-2022   |   Base Year: 2021   |   No Of Pages: 135   |   Historical Data: 2015 - 2019   |   Formats: PDF   |   Report ID: 24197423

Report DescriptionTable of Contents

The global protein expression market size was $2.45 billion in 2021 and is predicted to reach $6.47 billion by 2030, with a CAGR of 11.4% during the forecasted period 2021 - 2030. Based on Region, North America has considerable prospects for the market's major players.

 

Protein expression is a biotechnological process for manufacturing a particular protein obtained naturally by manipulating gene expression in an individual to produce huge amounts of a recombinant gene. The ageing population, rising incidence of chronic illnesses and increased investment in protein-based research is likely to fuel market revenue growth throughout the forecasted period. 

protein expression market by share 2020-2030

Market Dynamics:

Market Drivers: - (Increasing occurrence of target illnesses, great effectiveness of protein therapies, higher adoption rate)

  • The rising cases of illnesses such as cancer, cardiovascular disease, and genetic disorders are propelling the protein expression system market forward. Protein-based medications, such as insulin, for example, can cure a wide range of ailments with amazing efficacy.

 

  • Furthermore, businesses are investing in protein expression systems research such as baculovirus expression systems (Insect cell expression systems), transient expression (Mammalian cells), and stable expression. Because of the great effectiveness of protein therapies, there is a low risk of adverse effects associated with protein therapeutics, which is driving the market growth significantly.

 

  • Also, the transient protein expression market is driving the global market with the advancement of genetic engineering, which has opened up a slew of new routes and opportunities for large-scale protein expression and isolation.

 

Market Restraints: - (Low R & D spending, high cost of research, lack of professionals) 

  • Low R & D spending, lack of standardization, lower rate of prevailing experts and the exorbitant cost of proteomics research are the crucial factors limiting the global industry growth.

 

Opportunities: - (Increasing incidence of chronic illnesses, the introduction of microfluidics, technological advancement) 

  • The rise in the incidence of chronic diseases is likely to increase the growth of the market throughout the forecasted period. Furthermore, the increased demand for protein biologics is expected to boost the market size in the future.

 

  • The introduction of microfluidics and the advancement of developing nations have provided a significant amount of development, which will create further chances for the protein expression systems market to grow in the future years.

protein expression market by application 2020-2030

Protein Expression Market Analysis Of Different Segments:

The Market segmentation analysis is based on System Type, Products and services, Application, End Users, and Region.

Based on System Type

  • Prokaryotic Expression Systems

  • Vagus Nerve Stimulation

  • Escherichia coli Systems

  • Other Systems

  • Yeast Cell Expression Systems

  • Kluyveromyces Lactis Systems

  • Saccharomyces Systems

  • Pichia Systems

  • Other Systems

  • Insect Cell Expression Systems

  • Baculovirus Expression Systems

  • Other Systems 

  • Cell-free Expression Systems

  • Algal-based Expression Systems (protein expression system in E. coli)

 

Based on Product and Service

  • Reagents

  • Expression Vectors

  • Competent Cells

  • Instruments

  • Services

 

Based on Application

  • Therapeutic Applications

  • Industrial Applications

  • Research Applications

 

Based on End-User

  • Pharmaceutical and Biotechnology Companies

  • Academic Research Institutes

  • Contract Research Organizations (CROs)

  • Other End Users

 

Based on Region

North America

  • US

  • Canada

  • Rest of North America

 

Europe

  • Germany

  • France

  • UK

  • Italy

  • Spain

  • Rest of Europe

 

Asia - Pacific

  • China

  • Japan

  • India

  • Australia

  • Rest of APAC

 

Rest of the World

  • Latin America

  • Middle East &

  • Africa

protein expression market by region 2020-2030

Based on System type, because of its wide acceptability, the cell-free protein expression has the largest market share, and this protein expression is carried out without the usage of live cells. This technology offers several benefits above other protein expression techniques and drives the industry technology, and it is commonly employed as a result of these advantages. The industry is growing due to cell-free protein approaches, such as enhanced speed, ability to produce hazardous proteins, and convenience of amino acid type-specific labelling.

 

Based on Product and Service, the reagents segment is predicted to rise at a CAGR of 8.9% during the projection period. Acids and bases, acrylamides, buffers, cell lysis of carbohydrates, detergents, general reagents, protease inhibitors, and solvents are used in the protein expression process. These reagents have been used in research, industry, and pharmaceutical manufacturing. As a result, the market growth is projected to be aided by repeated purchases of reagents for various applications.

 

Based on Application, the therapeutic segment is predicted to account for a major revenue share over the forecasted duration due to the adaption of protein in biologics production and growing preference for protein therapies to treat chronic diseases such as cancer, anaemia, haemophilia, multiple sclerosis, arthritis, and diabetes, among others.

 

Based on End User, Pharmaceutical and biotechnology firms accounted for a substantial revenue share in the worldwide market in 2020, according to the end-use industry segment. The segment's revenue growth is fuelled by rising demand for biopharmaceuticals, fast advances in protein-based research, and increased investment and support for medication design (newly developed c protein marker) and development.

 

Based on Region, North America has considerable prospects for the market's major players. Moreover, the fastest-growing industry in the Asia Pacific is predicted to grow at a strong 11.2 % CAGR throughout the projection period. Therefore, this area provides excellent protein market opportunities and is expected to develop at the fastest rate over the projected period.

 

Report Attribute

Details

Forecast Period

2021 - 2030

The market size value in 2021

USD 2.45 Billion

The revenue forecast in 2030

USD 6.47 Billion

Growth rate

CAGR of approximately 11.4%

The base year for estimation

2021

Unit

USD Billion, CAGR (2021 - 2030)

Segmentation

By Product and Service, By System Type, By Application, By End-user, By   Region

By Product and Service

Reagents, Expression Vectors, Competent Cells, Instruments, Services.

By End-user

Pharmaceutical and Biotechnology Companies, Academic Research Institutes, Contract Research Organizations (CROs), Other End Users.

By System Type

Prokaryotic Expression Systems, Vagus Nerve Stimulation, Escherichia coli Systems, Yeast Cell Expression Systems, Kluyveromyces Lactis Systems, Saccharomyces Systems, Pichia Systems, Insect Cell Expression Systems, Baculovirus Expression Systems, Other Systems, Cell-free Expression Systems, Algal-based Expression Systems.

By Application

Therapeutic Applications, Industrial Applications, Research Applications

By Region

Asia Pacific, North America, Europe, LAMEA

Country Scope

U.S., Canada, France, Germany, U.K., China, Japan, India, South Korea, Mexico, Brazil, U.A.E. etc.

Company Usability Profiles

Agilent Technologies Inc., Merck KGaA, Takara Bio Inc, New England Biolabs, BECTON, DICKINSON AND COMPANY, BIO-RAD LABORATORIES, INC., GenScript Biotech Corporation, LifeSensors Inc., Promega Corporation, QIAGEN NV., THERMO FISHER SCIENTIFIC, INC., Oxford Expression Technologies Ltd., Synthetic Genomics Inc.

 

Protein Expression Market Competitive Landscape Analysis

The competitive landscape analysis gives an overview of some prominent players operating in the market. Product innovation and continued R&D operations to create sophisticated technologies have assisted the growth. In the target market, there are many significant companies, and some of the market leaders are:

 

Recent Developments:

  • On 8th September 2021, Aviva Systems Biology, a global leader in antibodies, immunoassay kits, and recombinant proteins for life science research, announced the debut of their Protein on Demand service. Successful life science research requires high-quality recombinant proteins. While in-house protein manufacturing is possible, many laboratories and organizations lack the time or resources to do so. Aviva's launch of Protein on Demand semi-custom recombinant proteins intends to provide widespread access to the unique recombinant proteins required by academic researchers and small biotechs with ambitious research goals but limited resources.

 

  • On 21st June 2021, QIAprep&amp CRISPR Kit and CRISPR Q-Primer Solutions were released, allowing researchers to evaluate altered genetic material with unprecedented speed and efficiency to see how their interventions have impacted the function of the DNA sequence in the issue. The product's debut represents QIAGEN's first specialized solutions for the rapid field of CRISPR technology, which is used to edit genomes and adjust gene function.

 

  • On 27th January 2020, Merck announced a € 250 million investment in the Merck Biotech Development Center in Corsier-sur-Vevey, Switzerland, dedicated to biotech development and manufacturing for clinical trials. This project will help to sustainably secure capacity and high agility to deliver clinical trial material cost-effectively, contribute to accelerated development timelines for new biological entities, and identify the rising manufacturing complications of the next generations of biotech compounds, all driven by the growth of the Healthcare business sector R&D pipeline.

 

Various devices that the market leaders are manufacturing are:

 

Names

Features

Key Player

TnT SP6

 

Single tube translation system that expresses protein in concentrations of 10-100 µg/ml in two hours

Promega

 

pEXP1-DEST Vector

The ExpresswayTM Cell-free E. coli Production System allows for maximum expression of recombinant fusion proteins.

 

THERMO FISHER SCIENTIFIC, INC.

 

LB Agar Ampicillin-100

 

Used to make the RNAi library for Trypanosoma brucei

Sigma

 

 

Frequently Asked Question About This Report

b: Protein expression is a strategy for synthesizing, modifying, and regulating proteins in living organisms. Protein expression determines if one or more proteins are present in a cell or tissue. Pharmaceutical firms, biotechnology corporations, university research institutions, contract research organizations, and others employ protein expression for proteomics. And this market is called the protein expression market.

b: The global protein expression market share was USD 2.45 billion in 2021. However, it is predicted to reach USD 6.47 billion by 2030, with a CAGR of 11.4 % throughout the forecasted duration.

b: The global protein expression market is expected to grow at a compound annual growth rate (CAGR) of 11.4% from 2021 to 2030 to reach USD 6.47 billion by 2030.

b: S. cerevisiae is one of the best protein expression systems.

b: E. coli is one of the most commonly used protein expression systems.

b: Reducing the transcription rate, either by replacing a strong promoter with a weaker one or weakening a strong supporter by introducing a point mutation, can improve protein expression.

b: The global protein expression market size was $2.45 Bn in 2021 and is predicted to reach $6.47 Bn by 2030, with a CAGR of 11.4% during the forecasted period 2021 - 2030.

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